Serum Protein Electrophoresis
Department of Immunology
Notes
- This is a screening test for paraproteinaemia. It is carried out in conjunction with serum immunoglobulins.
- Both new and known paraproteins are quantified and any new paraproteins are typed to determine the heavy and light chain class.
- Can be used to screen for Myeloma and MGUS, known patients require paraprotein monitoring.
Sample Requirements
Adult
5ml Gold-top SST tube or 3.5ml Rust-top gel tube (Trust users only)
Paediatric
1ml Serum Sample
Assay interferences
Microbially contaminated, heat-treated, grossly haemolysed, icteric or lipaemic specimens should be avoided. Plasma is contraindicated as it contains a large fibrinogen band which may obscure a monoclonal band.
Turnaround Times
7 days