Lipoprotein (a)
Clinical Biochemistry
Background Information
- Lipoprotein (a) (Lp (a)) is a lipoprotein consisting of a lipid-rich core surrounded by two proteins, apolipoprotein B-100 and apolipoprotein (a).
- Lipoprotein (a) may be requested with other lipid tests in patients who have developed cardiovascular disease at a young age, or who have a family history of premature heart disease, to determine whether the concentration of lipoprotein (a) is contributing to the patient’s risk of cardiovascular disease.
- Lipoprotein (a) levels are largely genetically determined. Testing may be recommended if a first-degree family member has a high level of lipoprotein (a).
- Although some specialist doctors occasionally request lipoprotein (a), it is not a routinely used test and widespread testing is not currently recommended.
Lipoprotein (a) requesting is only recommended in specific circumstances. If there are any queries regarding the indications for this test please contact the GHNHSFT lipid clinic team.
Patient Preparation
No specific preparation required
Sample requirements
For adults, 5 ml of blood taken into a narrow plain gold top gel tube.
There is usually no indication for repeat testing of lipoprotein (a)
Storage/Transport
Do not store. Send to the laboratory at room temperature on the day of venepuncture. Samples must be centrifuged and serum separated from red cells in less than 12 hours.
Required Information
Please include relevant clinical details including the reason for the request, family history, current lipid-lowering medication and date and time of sample.
Turnaround Times
Samples are referred to an external laboratory for analysis with results expected back within 7 working days.
Reference Ranges
Ranges and interpretation reported as provided by referral laboratory.
Further Information
To learn more about this test, please visit Lab Tests Online
Page last updated: 23/10/2025 | Page last reviewed: 23/10/2025